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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
GSK-963 Chemical Structure
BCP37994 GSK-963 2049868-46-2
GSK-963 is a potent and selective inhibitor of RIP1 kinase.
GSK962 Chemical Structure
BCP37995 GSK962 2049872-86-6
GSK962 is a negative control for GSK'963, a highly potent and selective RIP1 inhibitor.
GSK-843 Chemical Structure
BCP37845 GSK-843 1601496-05-2
GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM.
CRT5 Chemical Structure
BCP37818 CRT5 1034297-58-9
CRT5 is a pyrazine benzamide that prevents activation of all three isoforms of PKD in endothelial cells treated with VEGF (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively).
(Rac)-Benpyrine Chemical Structure
BCP37768 (Rac)-Benpyrine 1333714-43-4
(Rac)-Benpyrine is a racemate of Benpyrine. (Rac)-Benpyrine is a potent and orally active TNF-α inhibitor and has the potential for TNF-α mediated inflammatory and autoimmune disease research.
Ac-YVAD-CMK Chemical Structure
BCP37297 Ac-YVAD-CMK 178603-78-6
Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1).
iFSP1 Chemical Structure
BCP37001 iFSP1 150651-39-1
iFSP1 is a ferroptosis suppressor protein 1 (FSP1) inhibitor and ferroptosis inducer.
PROTAC MDM2 Degrader-2 Chemical Structure
BCP36817 PROTAC MDM2 Degrader-2 2249944-99-6
PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology.
Bcl-2-IN-2 Chemical Structure
BCP36375 Bcl-2-IN-2 2383085-86-5
Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL.
BCL2 Degrader C5 Chemical Structure
BCP36383 BCL2 Degrader C5 2378801-85-3
BCL2 Degrader C5 is a novel potent and selective degrader of Bcl-2.
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