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SARS CoV

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SARS CoV

Chemical Structure Cat. No. Product Name CAS No.
FOY 251 mesylate Chemical Structure
BCP37774 FOY 251 mesylate 71079-09-9
FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.
PLpro inhibitor Chemical Structure
BCP37597 PLpro inhibitor 1093070-14-4
PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with an IC50 of 2.6 μM. PLpro inhibitor inhibits SARS-CoV-2 PLpro with an IC50 of 5.0 μM and an EC50 of 21.0 μM.
Favipiravir Chemical Structure
BCP02422 Favipiravir 259793-96-9
Favipiravir, also known as T705, is a RNA-directed RNA polymerase NS5B inhibitor
Favipiravir Ribofuranose Chemical Structure
BCP36535 Favipiravir Ribofuranose 356782-88-2
T-705 Ribofuranose is a reagent used for the preparation of pyrazine-ribofuranose derivatives as antiviral agents that are useful in the treatment of viral infections.
GS-704277 Chemical Structure
BCP35774 GS-704277 1911579-04-8
GS-704277 is an alanine metabolite of Remdesivir.
GS441524 Chemical Structure
BCP35590 GS441524 1191237-69-0
GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.
Zotatifin Chemical Structure
BCP35487 Zotatifin 2098191-53-6
Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis (IC90=37 nM). Zotatifin induces cell apoptosis.
GRL0617 Chemical Structure
BCP33895 GRL0617 1093070-16-6
GRL-0617 is a potent, noncovalent SARS-CoV papain-like protease (PLpro) inhibitor with IC50 of 0.6 uM, Ki of 0.49 uM.
XP-59 Chemical Structure
BCP33880 XP-59 890402-73-0
XP-59 is a potent inhibitor of the SARS-CoV Mpro.
ML188 Chemical Structure
BCP33267 ML188 1417700-13-0
ML188, a first in class probe, is a selective non-covalent SARS-CoV 3CLpro inhibitor with an IC50 of 1.5 μM. Antiviral activity.
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