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TRP Channel

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TRP Channel

Chemical Structure Cat. No. Product Name CAS No.
GSK2798745 Chemical Structure
BCP38659 GSK2798745 1419609-94-1
GSK2798745 is a potent and selective TRPV4 Ion Channel Inhibitor with IC50 = 1.8 nM.
AM12 Chemical Structure
BCP37833 AM12 2387510-84-9
AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM.
AC1903 Chemical Structure
BCP37804 AC1903 831234-13-0
AC1903 is a specific blocker of TRPC5 channel activity. It has been shown to suppress severe proteinuria and prevent podocyte loss.
GSK2193874 Chemical Structure
BCP36070 GSK2193874 1336960-13-4
GSK2193874 is an orally active, potent, and selective TRPV4 antagonist with IC50s of 2 nM and 40 nM for rTRPV4 and hTRPV4.
Adenosine 5'-diphosphoribose sodium salt Chemical Structure
BCP35556 Adenosine 5'-diphosphoribose sodium salt 68414-18-6
Adenosine 5′-diphosphoribose sodium is a nicotinamide adenine nucleotide (NAD+) metabolite.
Pico145 Chemical Structure
BCP35558 Pico145 1628287-16-0
Pico145, also known as HC-608, is a potent inhibitor of TRPC1/4/5 channels.
BI-749327 Chemical Structure
BCP34713 BI-749327 2361241-23-6
BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively.
ASP7663 Chemical Structure
BCP33952 ASP7663 1190217-35-6
ASP7663 has been found to be a TRPA1 activator and could show abdominal analgesic activities.
PF-04745637 Chemical Structure
BCP33691 PF-04745637 1917294-46-2
PF-04745637 is a TRPV1 antagonist.
MDR-652 Chemical Structure
BCP33294 MDR-652 1933528-96-1
MDR-652 is a nonpungent transient receptor potential vanilloid 1 (TRPV1) agonist discovered to be a strong topical analgesic.
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